Tuesday's scheduled four-hour visit is to be Mr. Obama's first to Georgia since taking office and is billed as part of his "White House to Main Street" tour.
The White House said Mr. Obama's visit will focus heavily on Savannah Technical College.
Mr. Obama is scheduled to tour the college Tuesday morning before going to Hunter Army Airfield shortly before noon. He will tour Savannah and then depart from Hunter before 4 p.m.
White House officials say it's part of President Obama's efforts to get outside Washington and "talk to American families about what they are experiencing during these tough economic times."
The president will make a series of local stops to speak to students and workers, meet with Savannah residents and tour local businesses.
Ever since his State of the Union address last month, Mr. Obama has repeatedly said he wanted to spend more time outside of Washington.
Savannah's port is a major international trade hub also could have been picked after President Obama talked about the need to boost trade abroad.