Atlanta Firefighters responded to a report of a white powdery substance found in an envelope at a state building on Monday.
News Chopper 2 showed emergency crews entering the Sloppy Floyd Building on Jesse Hill Jr. Drive in downtown Atlanta.
Officials said no one was evacuated from the building and they later determined the substance was pain medication.
A spokesman for the Georgia State Patrol said the package and the two employees were isolated for a short time.
A fire department official told Channel 2's Dave Huddleston a similar package was sent to a state office building in Baltimore, Md. but the incidents have not been linked.