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"Big Shots" Makes Big Splash Tonight

Thursday, September 27, 2007 – updated: 6:53 am EDT September 27, 2007

If you can imagine "Sex and the City" with four guys instead of the women, that's the premise of "Big Shots."

The show premieres Thursday night on WSB-TV Channel 2 at 10 p.m.

The quartet is played by Joshua Molina, Christopher Titus, Dylan McDermott and Michael Vartan.

But before "Big Shots" takes its shot, the new season of "Ugly Betty" begins at 8 p.m.

Thursday night she tries to start fresh and forget about Henry.

Next is "Grey's Anatomy" at 9 p.m.

The interns are now residents. Except for George. He has to repeat his final year as an intern. And, Chyler Leigh joins "Grey's" as Meredith's half-sister.